Hepatopulmonary syndrome associated with iron overload in sickle cell anaemia
نویسندگان
چکیده
منابع مشابه
Hepatopulmonary syndrome associated with iron overload in sickle cell anaemia.
At present, it is estimated that 10,000 to 20,000 patients in the USA are treated with long-term blood transfusion [1], including patients with sickle cell disease (SCD) who are often transfused to prevent stroke [2, 3]. Iron overload is common in patients with recurrent transfusion, and the degree of iron overload may correlate with the rate of transfusions [4, 5]. While iron overload and cirr...
متن کاملIron Overload in Sickle Cell Disease
In sickle cell disease transfusions improve blood flow by reducing the proportion of red cells capable of forming sickle hemoglobin polymer. This limits hemolysis and the endothelial damage that result from high proportions of sickle polymer-containing red cells. Additionally, transfusions are used to increase blood oxygen carrying capacity in sickle cell patients with severe chronic anemia or ...
متن کاملCardiac iron overload in chronically transfused patients with thalassemia, sickle cell anemia, or myelodysplastic syndrome
The risk and clinical significance of cardiac iron overload due to chronic transfusion varies with the underlying disease. Cardiac iron overload shortens the life expectancy of patients with thalassemia, whereas its effect is unclear in those with myelodysplastic syndromes (MDS). In patients with sickle cell anemia (SCA), iron does not seem to deposit quickly in the heart. Our primary objective...
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Introduction: Eastern India -the melting pot of different heterozygous Sickle cell syndrome. Mostly NTDT, we wanted to study the pattern of iron overload in this heterogeneous yet homogenous group of patients. As there is no such study from this part of the world, it would reveal the true state of iron overload, appropriate test/s and chelation requirement. Methodology: 152 subjects of Sickle c...
متن کاملIron deficiency anaemia in sickle cell disorders in India.
BACKGROUND & OBJECTIVE Iron deficiency anaemia (IDA) is uncommon in individuals with sickle cell disease (SCD) because of availability of an adequate iron source potentially from increased red cell turnover and from blood transfusions. Also, iron deficiency anaemia can often go unnoticed because the sickle cell disease patients are already anaemic. Iron deficiency in sickle cell patients may re...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2012
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.00199411